Download The Blood Group Antigen Facts: Book by Marion E. Reid PDF

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By Marion E. Reid

The second one version of The Blood crew Antigen FactsBook offers key info when it comes to human pink blood telephone membrane elements wearing blood crew antigens, the molecular foundation of the antigens, their serological features, and the scientific value of blood workforce antibodies. the knowledge in this staff of molecules has elevated significantly because the prior variation used to be released 5 years in the past. subject matters contain: background and data on terminology, expression, chromosomal task, service molecule description, molecular foundation of antigens, impression of enzymes/chemicals, scientific value, affliction organization, phenotypes, glycotypes and key references.

  • Over 250 totally up to date entries on blood team antigens, formatted on unmarried pages for simple use
  • Inclusion of RHAG blood team method and over twenty new antigens
  • Basic technological know-how paired with medical functions to offer context to information
  • Full-color illustrations, gene maps and charts
  • Both conventional and ISBT-sanctioned naming conventions included

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Extra info for The Blood Group Antigen Facts: Book

Sample text

C. et al. (2002) Immunohematology 18, 37–39. Swanson, J. A. (1962) Vox Sang. 7, 585–590. A. et al. (1965) Vox Sang. 10, 206–207. 1% in Caucasians, 2% in Asians and 6% in Japanese. He(Cal) 99 COOH COOH The Sta antigen arises when amino acid at residue 26 of GPB or GPA joins to GPA at residue 59. qxd 7/3/03 7:20 PM Page 61 MNS blood group system Effect of enzymes/chemicals on Sta antigen on intact RBCs Ficin/papain Trypsin ␣-Chymotrypsin Pronase Sialidase DTT 200 mM Acid Variable Resistant Resistant Sensitive Presumed resistant Resistant Resistant In vitro characteristics of alloanti-Sta Immunoglobulin class Optimal technique Complement binding IgM; IgG RT; IAT No Clinical significance of alloanti-Sta No data are available.

1971) Am. J. Hum. Genet. 23, 612–613. 01%. Antithetical antigen Vw (MNS9); ENEH (MNS40) Expression Cord RBCs Expressed Molecular basis associated with Hut antigen1,2 Amino acid Nucleotide Variant glycophorin Gene arrangement Mechanism Lys 28 of GPA A at bp140 in exon 3 GPA(1–27)-GPB(28)-GPA(29–131) GYP(A-␺B-A) Gene conversion or a single nucleotide substitution in GYPA The N-glycosylation consensus sequence is changed so that Asn 26 is not Nglycosylated, which results in a decreased Mr of about 3000.

Production of mono clonal anti-Mia (GAMA 210 and CBC-172) showed that anti-Mia exists as a single specificity and that Mia is a discrete antigen3. Mur phenotype RBCs in antibody investigations. References 1 2 3 4 5 Tippett, P. et al. (1992) Transf. Med. Rev. 6, 170–182. Dahr, W. (1992) Vox Sang. 62, 129–135. Chen, V. et al. (2001) Vox Sang. 80, 230–233. H. et al. (1994) Transfusion 34, 238–241. E. and Lin, M. (1994) Transfusion 34, 349–352. 008) Mc was described in 1953. The antigen appeared to be intermediate between M and N, and as such, was analogous to the situation described in 1948 for the Rh antigen cv; hence the name Mc was used.

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