By William F. Kern MD
PDQ Hematology is a concise and concentrated creation to scientific hematology. It succinctly covers an important facets of the sphere with an emphasis on medical positive factors, prognosis, and therapy. PDQ Hematology completely examines these stipulations often encountered by way of physicians and contains basic rules for more odd or advanced ailments. The textual content additionally features a dialogue of malignant lymphomas in addition to the standard medical hematology subject matters (such as anemia and leukemia). The large use of tables and diagrams make this moveable ebook an available and sensible spouse.
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To be sure that iron is completely absent, an iron stain must be done on an aspirate smear or aspirate clot section that has not been decalcified. ➪ An elevated zinc erythrocyte protoporphyrin level (ZEP, also called free erythrocyte protoporphyrin) has been recommended as a screening test for iron deficiency since it is very sensitive and can be easily and inexpensively measured. However, it is also elevated in anemia of chronic disease, lead poisoning, and other conditions. It is therefore useful in screening populations for iron deficiency (since iron deficiency is the most common cause of elevated ZEP in the general population) but is less useful in diagnosis of the individual patient.
5 mg per day in conditions of iron excess. Dietary iron is considered to be of two types: heme iron and nonheme iron. Heme iron is easily and efficiently absorbed into the mucosal cells, and absorption is not affected by other components of the diet. Nonheme iron is absorbed much less efficiently and can be inhibited by many dietary factors. Heme iron comes from meat. It represents about 10 to 15% of dietary iron in the United States—less in underdeveloped countries, where meat is a smaller part of the diet.
Repeat radiographs can be used to determine the effectiveness of lavage. Blood should be drawn for serum iron at ~3 to 5 hours and ~6 to 8 hours after ingestion. Levels of <350 g/dL generally indicate minimal toxicity, levels of 350 to 500 g/dL are associated with moderate toxicity, and levels >500 g/dL may be lethal. Deferoxamine, an iron chelator, may be given intravenously at a rate of 15 mg/kg body weight per hour for severe poisoning. Standard supportive measures for hypotension, shock, and acidosis should also be employed.