By J. Oertel, D. Huhn (auth.), Professor Dr. med. Dieter Huhn (eds.)
This e-book describes the most recent tools in oncological and hematological diagnostics, together with immunological, molecular genetic and cytogenetic assays. All equipment are defined of their assorted diversifications and in comparison when it comes to expense and effectiveness. every one bankruptcy ends with an in depth "how-to-do" part. The publication is written for scientists, clinicians and body of workers from learn and from regimen laboratories. It satisfies the expanding call for for info on new equipment in hematology and oncology.
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Additional resources for New Diagnostic Methods in Oncology and Hematology
Immunoperoxidase staining (anti-cyclin Dl) of a lymph node aspirate from a patient with mantle cell lymphoma Fig. 21. APAAP immunostaining (anti-CD103) of mononuclear blood cells from a patient with hairy cell leukemia 20 J. OERTEL, D. HUHN ble. The hairy cell marker CD 103 is positive in 15%, the markers CD2S, CD 10, CDS and CD23 in a minority of cases . 6 Follicle Center Lymphoma According to morphological criteria three cytologic grades are distinguished: grade 1 (predominantly small cell); grade 2 (mixed small and large cell); grade 3 (predominantly large cell).
These markers, however, are not specific for this disorder. Hairy cell leukemia variant is a very rare lymphoproliferative disorder. The morphological feature is intermediate between prolymphocytes and hairy cells. The nucleolus is more prominent than in SLVL. The hairy cell marker CD 103 is positive in some cases. There is no marker profile characteristic for this disorder. 5 Marginal Zone Lymphoma The entity may be nodal or extranodal (lymphoma of mucosa associated lymphatic tissues). Marginal zone lymphoma may be of indolent (small cell) or aggressive (large cell) type.
Mason DY, Cordell IL, Abdulaziz Z et al. (1982) Preparation of PAP complexes for immunohistological labelling of monoclonal antibodies. I Histochem Cytochem 30:1114-21 7. Woods IC, Harris H, Springs AI et al. (1982) A new marker for human cancer cells. 3. Immunocytochemical detection of malignant cells in serous fluids with the Cal antibody. Lancet 1:512-515 8. Bisgaard K, Lihme A, Rolsted H et al. (1993) Polymeric conjugates for enhanced signal generation in enzyme immunoassays. Abstract Scand Soc Immunol, XXIV Annual Meeting University of Aarhus Denmark May 22-26, 1993 9.