By Michael Boyiadzis, James Frame, David R. Kohler, Tito Fojo
The crucial remedy consultant to melanoma, Hematologic problems, and Supportive Care--Updated with the newest remedy Regimens
More than 500 therapy regimens
Hematology-Oncology Therapy, moment version is an updated, complete remedy consultant that gives you greater than 500 therapy regimens in a succinct, uniform demeanour. the original tabular layout lets you immediately find and enforce the correct remedy routine. Supported via the newest perform instructions, peer-reviewed literature, and the opinion of specialists, Hematology-Oncology Therapy integrates large details that's serious to either place of work- and hospital-based perform of hematology and oncology.
Hematology-Oncology remedy is split into 3 sections:
presents distinct information regarding the management, supportive care, toxicity, dose amendment, tracking, and efficacy of widely used and lately licensed chemotherapeutic regimens, medicinal drugs, and organic brokers
Supportive Care, Drug guidance, issues, and Screening:
involves themes usually encountered in scientific hematology-oncology perform, akin to chemotherapy-induced nausea, oncologic emergencies, radiation problems, melanoma ache administration, melanoma screening, and lots more and plenty extra
Selected Hematologic Diseases:
provides an authoritative consultant to remedy for the imperative illnesses in consultative hematology
This variation of Hematology-Oncology Therapy is enriched by way of the updating of all chapters in addition to the addition of numerous new chapters; the hot "Expert Opinion," which supplies concepts and counsel from specialists at the use of therapy regimens; and inclusion of the most recent regimens.
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Additional info for Hematology - Oncology Therapy
9 per 100,000 female Deaths: Estimated 950 in 2014 (male: 370; female: 580) Median age at diagnosis: 60 years Male to female ratio: Slight female predominance Stage at Presentation Stages I/II: 50% Stage III: 29–40% Stage IV: 10–13% Daling JR et al. J Natl Cancer Inst 2000;92:1500–1510 Fred Hutchinson Cancer Research Center, Changing Trends in Sexual Behavior May Explain Rising Incidence of Anal Cancer Among American Men and Women. org). 2004-07-06. Retrieved 2010-04 Frisch M et al. Gynecol Oncol 2009;114:395–398 Maggard MA et al.
9% NS or 5% dextrose injection over 24 hours for 5 consecutive days, on days 1–5, every 4 weeks (total dosage/cycle ϭ 5000 mg/m2) Diarrhea Reduction in creatinine clearance* to Յ60% of on study value Delay therapy for 1 week. 66–1 mL/s) Consider reducing cisplatin dose, so that dose in milligrams equals the creatinine clearance* value expressed in mL/min†. 66 mL/s) Hold cisplatin Clinically signiﬁcant ototoxicity Discontinue cisplatin Clinically signiﬁcant sensory loss Discontinue cisplatin Notes: • Ten patients received further local treatment • Carboplatin used instead of cisplatin in the event of renal toxicity Supportive Care Antiemetic prophylaxis Emetogenic potential on days with cisplatin is HIGH.
Response assessment: Repeat imaging studies every 2 cycles; 24-hour urine cortisol and 17-hydroxycorticosteroids with each cycle if abnormal at baseline Notes The recommended limit for total cumulative lifetime doxorubicin dosage of 450–500 mg/m2 may be exceeded, provided that adequate cardiac monitoring is conducted before every or every other chemotherapy cycle ADRE NOCORTICAL CANCE R • S TREPTOZ OCIN ϩ M ITOTANE ADVANCED OR METASTATIC ADRENAL CANCER REGIMEN STREPTOZOCIN ؉ MITOTANE (Sz-M) Fassnacht M et al.