By Dionysios-Dimitrios Koutsouris, Athina A. Lazakidou
Concepts and traits in Healthcare info platforms covers the most recent examine subject matters within the box from top researchers and practitioners. This e-book deals theory-driven learn that explores the function of knowledge structures within the supply of healthcare in its diversified organizational and regulatory settings. as well as the embedded position of knowledge know-how (IT) in medical and diagnostics gear, details platforms are uniquely situated to trap, shop, approach, and converse well timed info to selection makers for greater coordination of healthcare at either the person and inhabitants degrees. for instance, information mining and choice aid functions can establish capability adversarial occasions for someone sufferer whereas additionally contributing to the population’s wellbeing and fitness via offering insights into the reasons of illness issues. info platforms have nice capability to lessen healthcare bills and increase results. The healthcare supply platforms percentage comparable features with so much provider and effective firms, but additionally show particular features, that are on the topic of the complexity and variety of healthcare creation, together with the distinctive methods healthcare execs discharge their medical projects. New necessities and technological advances happening in healthcare, details platforms, and data know-how have stimulated the evolving function of healthcare details platforms and similar know-how, and this publication may help carry the sector as much as date.
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The workflow starts with the user submitting a query via the search input field from the search engine started from the PONTE Authoring Tool (1). The search engine component selects from the indexed document store (2)—a subset of the clinical and nonclinical data sources (3)—those documents that are annotated with the relevant terms from the PONTE Ontology (4). Depending on the preferences the user may have selected via the PONTE Authoring Tool, the whole PONTE Ontology, only 32 A. Tagaris et al.
Randomized controlled trials are based on power analysis which determines the chance of detecting a truepositive result. Today, a study is considered as adequately powered if it has at least 80 % chances of detecting a clinically significant effect when one exists. To calculate a study’s power to detect a given effect, variables are being used, including the number of participants, the expected variability of their outcomes and the chosen probability of making a false positive conclusion (type I error).
3 Drug Repositioning Within this context and with the reduction of drug approvals, the intensified competitive environment that blockbuster products are requested to survive within and the gradually reducing funding for new research within the field due to the global financial shrinkage, drug repositioning comprises a current trend that pharma companies tend to follow to gain more profits from drugs that either are about to go off patent or are already off-patent. Gathering data on potential application of drugs to new diseases and disorders is nowadays not only a means for evaluating the effectiveness of new medicine and pharmaceutical formulas but also for experimenting on existing drugs and their appliance to new diseases and disorders.