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By Roger L. Lundblad

''Discussing the position of plasma proteins in present biotechnology, this ebook describes the protein composition of human plasma, the fractionation of plasma to procure healing proteins, and the research of those items. It delineates the trail from plasma items to recombinant items, and highlights items from albumin, intravenous immunoglobins, and coagulation. It bargains a entire assessment of current Read more...

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Biotechnology of plasma proteins

''Discussing the function of plasma proteins in present biotechnology, this booklet describes the protein composition of human plasma, the fractionation of plasma to procure healing proteins, and the research of those items. It delineates the trail from plasma items to recombinant items, and highlights items from albumin, intravenous immunoglobins, and coagulation.

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Dis. 16, 617–638, 1993. 1–7 It is also clear that the development of blood collection and storage method was essential to the provision of plasma for fractionation. It is useful then to briefly consider the history of transfusion medicine as a preamble to plasma fractionation and plasma protein products. 9 Ficarra noted both the historical importance of blood in human sacrifice and the custom of oral blood consumption as a therapeutic. Considering the current interest in the oral delivery of protein therapeutics,10,11 the oral consumption of blood is an early example of this technology.

23, 219–238, 1916. 29. , Preservation of red blood cells for transfusion, Hum. Pathol. 14, 213– 217, 1983. 30. N. , The development and acceptance of the anticoagulant, CPD, Vox. Sang. 48, 122–125, 1985. 31. , The introduction of citrate as an anticoagulant for transfusion and of glucose as red cell preservative, Brit. J. Haematol. 108, 13–18, 2000. 32. , The therapy of the Cook County Hospital, J. Am. Med. Assoc. 109, 128–131, 1937. 33. D. , Churchill Livingstone/Elsevier, Philadelphia, 2007. 34.

140. , High dynamic range characterization of the trauma patient plasma proteome, Mol. Cell. Proteomics 5, 1899–1913, 2006. 141. , Mapping the human plasma proteome by SCX-LC-IMS-MS, J. Am. Soc. Mass Spectrom. 18, 1249–1264, 2007. 142. , Calorimetric analysis of the plasma proteome, Sem. Nephrol. 27, 621–626, 2007. 143. , Comparative human salivary and plasma proteome, J. Dent. Res. 89, 1016–1023, 2010. 144. , The human plasma proteome, Mol. Cell. Proteomics 3, 311–326, 2004. 145. , A high-confidence human plasma proteome reference set with estimated concentrations in PeptideAtlas, Mol.

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