By Clifford Smith, Alfred Jarecki(auth.)
A necessary source on blood and bone marrow cellphone morphology in laboratory animal medication. This absolutely revised re-creation is a necessary reference for medical pathologists in diagnostic laboratories, and scientific or veterinary examine. The atlas comprises over four hundred colour photographs of cells from the peripheral blood and bone marrow from quite a few animals encountered in laboratory animal drugs, in healthiness and illness.
Key positive aspects:
- New bankruptcy on stream cytometry and its software by way of regimen analyses as a way of deciding on abnormalities in mobile marker expression, that is of specific relevance for pre-clinical security overview
- Covers the newest advancements in laboratory animal hematology, together with parameters measured through the most recent new release of analyzers
- Coverage of quite a lot of laboratory animal species, in addition to these utilized in scientific veterinary trials
- Photomicrographs current basic and irregular blood cells from a number of hematological stipulations in addition to descriptive textual content
Chapter 1 Rodents (pages 1–36): Clifford Smith and Alfred Jarecki
Chapter 2 Rabbit (pages 37–39): Clifford Smith and Alfred Jarecki
Chapter three Cat (pages 41–44): Clifford Smith and Alfred Jarecki
Chapter four puppy (pages 45–64): Clifford Smith and Alfred Jarecki
Chapter five Monkey (pages 65–87): Clifford Smith and Alfred Jarecki
Chapter 6 different Species (pages 89–103): Clifford Smith and Alfred Jarecki
Chapter 7 Blood assortment systems (pages 105–106): Clifford Smith and Alfred Jarecki
Chapter eight Artifacts (pages 107–114): Clifford Smith and Alfred Jarecki
Chapter nine Bone Marrow (pages 115–120): Geoff Brown
Chapter 10 Comparative functions in move Cytometry (pages 121–133): Alaa Saad
Read Online or Download Atlas of Comparative Diagnostic and Experimental Hematology, Second Edition PDF
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Extra resources for Atlas of Comparative Diagnostic and Experimental Hematology, Second Edition
75 Rat: peripheral blood. Early lymphocyte with hyperchromia, polychromasia, crenation and a Howell–Jolly body (arrow) (×1000). 78 Rat: peripheral blood. Nucleated red cells, polychromasia and anisocytosis (×500). 76 Rat: peripheral blood. Neutrophil and lymphocyte (×500). 79 Rat: peripheral blood. Extreme polychromasia and low platelet count (×500). 80 Rat: bone marrow. Howell–Jolly bodies (arrowed) (×1000). 83 Rat: bone marrow. Plasma cell excess (×500). 81 Rat: bone marrow. Leukemoid reaction; myeloblast hyperplasia (×1000).
Precipitation of globular material and associated neutrophilia. This unusual phenomenon appeared at room temperature and may reflect an interaction between the administered compound and plasma proteins (×1000). 127 Rat: peripheral blood. Artifact Hb crystals caused by partial freezing of the sample (×1000). 128 Rat: peripheral blood. Artefact Hb crystals caused by partial freezing of the sample (×1000). 131 Rat: peripheral blood. Intra-erythrocytic Hb crystals (electron microscope (EM)). 129 Rat: peripheral blood.
They are generally larger than neutrophils with small, round, strongly acidophilic granules which fill the cytoplasm. Immature nuclei often appear “doughnut shaped”. Care must be taken when assessing data from stored samples analysed on automated analysers as degraded neutrophils may be mistaken for monocytes and eosinophils and the differential may be inaccurate. Microscopic evaluation is therefore critical to ensuring the integrity of these counts. Basophils are uncommon, or absent, in rat blood preparations in some strains.