By Johannes W. Rohen MD, Chihiro Yokochi MD, Elke Lütjen-Drecoll MD
This atlas good points awesome full-color pictures of tangible cadaver dissections, with accompanying schematic drawings and diagnostic photos. the pictures depict anatomic buildings extra realistically than illustrations in conventional atlases and express scholars precisely what they'll see within the dissection lab.
Chapters are equipped by way of sector so as of a customary dissection. each one bankruptcy offers constructions either in a systemic demeanour from deep to floor, and in a local manner.
This version has 16 extra pages of medical images—including CT and MRI—that scholars can evaluate with cross-sectional anatomic photos. Many images were electronically superior or rescanned for larger contrasts.
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Studies using polarized light and X-rays have shown that the myelin sheath is made up of alternating layers of protein and lipid molecules. Accordingly, the dark lines (major period line and intraperiod line) are regarded as layers of protein molecules and the light lines as layers of lipid molecules. At regular intervals (1 – 3 mm), the myelin sheath is interrupted by deep constrictions, the nodes of Ranvier (AB4 F). The segment between two nodes of Ranvier in peripheral nerves, the internode or interannular segment (F), corresponds to the expansion of one sheath cell.
The synapse consists of the presynaptic component (bouton) (AB1) with the presynaptic membrane (BC2), the synaptic cleft (B3), and the postsynaptic component with the postsynaptic membrane (BC4) of the next neuron. The bouton is free of neurofilaments and neurotubules but contains mitochondria and small, mainly clear vesicles (BC5) which are clustered near the presynaptic membrane (active zone). The synaptic cleft contains filamentous material and communicates with the extracellular space. The presynaptic and postsynaptic membranes exhibit dense zones of apposition, which resemble those found at various cell junctions (zonulae or maculae adherentes, adherent junctions or desmosomes).
By contrast, the capillary walls of many other organs (liver, kidney [E8]) exhibit prominent fenestration which allows for extensive metabolite exchange. The barrier effect has been demonstrated for numerous substances in studies using isotopes. The barrier may result in a complete blockade or in a delay of penetration. Whether or not drugs can penetrate this barrier has major practical implications. The sealing of the brain tissue from the rest of the body manifests itself in the blood– brain barrier, a selective barrier for numerous substances that are prevented from penetrating from the bloodstream through the capillary wall into the brain tissue.